Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing
articles matching metastatic — open any to read the full text,
or download the PDF or XML.
May 2023
Fadoua BouguerraCorresponding author
Background and Aim Breast cancer is the second most common cause of brain metastases after lung cancer. However, the incidence of cerebral metastases from breast cancer has increased during the last years. The purpose of this study is to determine the prognostic value of chemotherapy after whole-bra…
Mar 2022 DOI 10.14302/issn.2641-5518.jcci-22-4097
Julian Iñaki L. GarciaCorresponding author
Malignant melanoma the most common malignancies associated with GI involvement. They usually manifest clinically at an advanced stage of neoplasm. Surgery is also recommended for palliative treatment of GIT metastases. A case of a 67-year-old male diagnosed with malignant melanoma for 7 months had b…
Dec 2015 DOI 10.14302/issn.2574-4496.jtc-15-779
Xiaoqi LinCorresponding author
It is extremely rare that sarcomas metastasize to the thyroid. We report a case of a 49 year old male with malignant peripheral nerve sheath tumor (MPNST) metastatic to the thyroid that was diagnosed by ultrasound guided fine needle aspiration (FNA). The FNA cytology showed numerous loosely cohesive…
Oct 2015 DOI 10.14302/issn.2379-8572.joa-15-691
Hany Abdel RahmanCorresponding author
Background. Nasopharyngeal carcinoma (NPC) is a rare disease in the pediatric age group; it represents 1% of all pediatrics malignancies, however, it is the predominant malignancy arising in the nasopharynx in this age group. Although NPC is a chemo-radiosensitive disease yet, the optimal dose of ra…
Jul 2026 DOI 10.14302/issn.2690-4721.ijcm-26-6132
K MirlekarCorresponding author
Burkholderia cepacia complex was isolated from pericardial fluid in a patient with metastatic lung adenocarcinoma, representing a rare opportunistic pericardial infection. Clinical improvement following targeted antimicrobial therapy supported its pathogenic significance and highlights the importanc…
Jun 2026 DOI 10.14302/issn.2574-4496.jtc-26-6304
Omayma ElshafieCorresponding author
Objective To evaluate the treatment outcomes of patients with Differentiated thyroid cancer (DTC) who underwent total thyroidectomy followed by RAI therapy at the Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC) in Oman. Methods This is a retrospective observational clinical stu…
Aug 2025 DOI 10.14302/oap.jpan-25-5589
Paul ToomeyCorresponding author
Background This study was undertaken to delineate the most predictive pattern at presentation for patients with non-metastatic pancreatic cancer compared to patients with metastatic pancreatic cancer who present to a medium sized hospital. Methods Data were collected at a medium sized hospital from…
May 2025 DOI 10.14302/issn.2379-8572.joa-25-5504
Mohamed HachemiCorresponding author
Introduction Angiosarcoma is a rare malignant tumour from fast-evolving and aggressive vascular endothelial cells that accounts for 1% of all sarcomas. The sinus location of angiosarcoma is exceptional. The clinical polymorphism of this tumour may cause a delay in diagnosis. Risk factors are not alw…
Mar 2024 DOI 10.14302/issn.2572-3030.jcgb-24-4970
Sarah DegenhardtCorresponding author
Melanoma treatment has improved significantly with the development of immune checkpoint inhibition (ICI), which has greatly enhanced the survival rates of patients with metastatic melanoma. However, a significant number of patients do not respond well to ICI treatment and experience progression. Thi…
Sep 2023 DOI 10.14302/issn.2574-4496.jtc-23-4722
Patrick J. ConwayCorresponding author
Background Patients with distant metastatic Medullary Thyroid Carcinoma (MTC) have an estimated 40% ten-year survival rate. Gain of function mutations in the REarranged during Transfection or RET gene in MTC can result in an aggressive phenotype resistant to traditional therapy. In this case report,…
Sep 2023 DOI 10.14302/issn.2641-5518.jcci-23-4743
Jonathan FarshadmandCorresponding author
Pancreatic adenocarcinoma is one of the leading causes of cancer-related death in the United States. Rarely, a tumor at the head of the pancreas can invade adjacent structures to cause a gastrointestinal bleed (GIB). We present a 78-year-old female whose massive upper GIB was the initial presentatio…
Jan 2022 DOI 10.14302/issn.2372-6601.jhor-22-4061
Anna B. DanilovaCorresponding author
Background Human malignant cell models which reflect the structural and physiological complexity of tumor tissue are of great importance for preclinical research in oncology. Spheroids/tumoroids derived from solid tumors are of great interest as cellular models mimicking the first vascular-free grow…
Jul 2020 DOI 10.14302/issn.2575-1212.jvhc-20-3434
Pamela R.R. MoreiraCorresponding author
Background The mammary glands are the second most common tumor development site in female dogs. One of the ways of staging such tumors is to evaluate the presence or absence of distant metastasis, including in bone marrow. Such findings in human medicine are associated with poor survival of women wi…
May 2019 DOI 10.14302/issn.2641-5518.jcci-19-2816
Menon P VarunCorresponding author
Assistant Professor, Department of Oral and Maxillofacial Surgery, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
Basal cell carcinoma (BCC) is the most common type of skin cancer, which arises from the basal layer of the epithelium. It is a slow growing tumor and has a low metastatic potential, it accounts for 70–80% of all cutaneous malignancies in the head face and neck region .Defects near nasal tip and ala…
Mar 2019 DOI 10.14302/issn.2642-9241.jrd-18-2499
Rodrigo A. S. SardenbergCorresponding author
Distant metastases generally indicate disseminated disease and the standard treatment for these patients is palliative chemotherapy. Retrospective series showed that selected patients with metastatic lung cancer and a solitary extrathoracic disease could be effectively treated with curative intentio…
Aug 2018 DOI 10.14302/issn.2639-1716.jn-18-2208
Gerald J. MizejewskiCorresponding author
Breast cancer (BC) is the leading cause of cancer-related deaths in young to middle-aged women worldwide. Moreover, the survival rate in BC-patients is only 20% when associated with metastatic disease. The high mortality rate observed in BC women with metastatic disease has precipitated a major chal…
Nov 2017 DOI 10.14302/issn.2471-2175.jdrt-17-1760
Madhuri BhandaruCorresponding author
Metastatic melanoma is a very deadly type of skin cancer with poor prognosis and low 5-year survival rates. Until recently, patients with metastatic melanoma had very few treatment options, which only included dacarbazine and aldesleukin. In 2011, the first checkpoint blocker, ipilimumab was approve…
Nov 2016 DOI 10.14302/issn.2574-4526.jddd-16-1311
M DarouichiCorresponding author
Department of radiology
Adenosquamous carcinoma of the stomach (ASCS) is extremely rare with less than one hundred cases published in the world literature. It is defined by combined adenocarcima and squamous cells carcinoma of the stomach. ASCS is clinically aggressive and has a poor prognosis, even when discovered at an e…
Aug 2016 DOI 10.14302/issn.2574-4496.jtc-16-1129
Frieda SilvaCorresponding author
Objective: Radiation exposure to the general public and patients undergoing diagnostic or therapeutic procedures is of great concern, especially to the medical community. Revision of Nuclear Regulatory Commission rules several years ago yield new recommendations for the administration of therapeutic…
May 2015 DOI 10.14302/issn.2471-7061.jcrc-14-574
Rosalyn B. IrbyCorresponding author
Colon cancer has a five-year survival of 64.7%, and about 50,000 people are expected to die from colon cancer this year. Patients with metastatic colorectal cancer have a significantly worse prognosis, a 12.9% five-year survival. This emphasizes the need for strategies to inhibit the growth and meta…