Search results for “iPSCs”

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Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching iPSCs — open any to read the full text, or download the PDF or XML.

2 articles

A Role for in Vitro Disease Models in the Landscape of Preclinical Cardiotoxicity and Safety Testing

Jul 2017 DOI 10.14302/issn.2574-4372.jesr-17-1705
Vijayalakshmi VarmaCorresponding author

Drug-induced cardiotoxicity is one of the predominant reasons for drug attrition and withdrawals. This is of critical concern when potentially cardiotoxic drugs are administered to individuals with inherited arrhythmogenic cardiac diseases or with metabolic diseases such as obesity and diabetes, whi…

Biocompatible Scaffolds for Human-Induced Pluripotent Stem Cell Transplantation and Modeling Post-Stroke Recovery in Three-Dimensional Neural Cell Culture

Jul 2016 DOI 10.14302/issn.2574-4372.jesr-16-1055
Matthew B. JensenCorresponding author

Human-induced pluripotent stem cells (HiPSCs) demonstrate promise in their ability to differentiate into neural cells and ultimately replace the cell types and thereby brain tissue damaged by stroke. This may diminish cognitive impairment due to stroke. Prior to transplantation, an appropriate scaff…

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