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Apr 2018
Jean-claude PEREZCorresponding author
The global analysis of 3 human genomes of increasing levels of evolution (neanderthal / sapiens build34 of 2003 / sapiens hg38 of 2013) reveals 2 levels of numerical constraints controlling, structuring and optimizing the DNA sequences of these genomes. A global constraint - which we will call "HGO"…
Apr 2018 DOI 10.14302/issn.2326-0793.jpgr-18-2004
Pervez AnwarCorresponding author
Human proteome project was revolutionized about 40 years ago with purpose of summarizing whole proteomic data at one place. It was launched after human genome project to map and observe all proteins. The goal related proteomic study is to draft the entire human proteome in disease diagnosis by using…
Mar 2018 DOI 10.14302/issn.2639-3166.jar-18-1987
Prem NarainCorresponding author
The scientific and technological interventions for attaining precision in plant genetics and breeding since Mendel’s discovery of genetic laws have been critically reviewed in terms of cloning technology and reverse genetics, chip technology, genetically modified organisms and CRISPR-based gene edit…
Nov 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1764
L. Miguel CarreiraCorresponding author
Leishmaniasis treatment monitoring is an important problem, since patient’s frequently present clinical signs improvements with positive indirect immunofluorescence (IFI) titers of anti-Leishmania antibodies, thus making difficult the clinician understand the therapy efficacy. The study aimed 1) to i…
Sep 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1694
R Berete CoulibalyCorresponding author
Introduction: Squamous cell carcinomas of the conjunctiva (SCC) are rare neoplasia but have a high rate of increase and a high rate of mortality, especially when they occur in the context of Human Immunodeficiency Virus (HIV) infection. The objective of this study was to establish an epidemiological…
Sep 2017 DOI 10.14302/issn.2575-7881.jdrr-17-1749
Kiran D. BhilareCorresponding author
Though, directed evolution/In vitro evolution has greatly enhanced the applicability of natural biomolecules, there is still a big void in synthetic biology, which could be filled only when we are able to make novel/synthetic functional biomolecules. Terminal deoxyribonucleotidyl transferase (TdT) i…
Aug 2017 DOI 10.14302/issn.2578-2371.jslr-17-1669
Aklesso BagnyCorresponding author
Aims: To describe the clinical, biological and evolutionary features of mono infected patients treated with tenofovir in Togo. Method: It is a descriptive, prospective study. Patients were treated with Tenofovir Disoproxil Fumarate (TDF). The inclusion criteria were: active chronic HBV (HBs Ag-posit…
Aug 2017 DOI 10.14302/issn.2638-4469.japb-17-1563
Dierk WankeCorresponding author
GAGA-binding proteins in plants are encoded by the BARLEY B-RECOMBINANT / BASIC PENTACYSTEINE (BBR/BPC) family, which can be spilt into several groups on the basis of sequence divergence. The proteins of the different groups share an evolutionary conserved BASIC PENTACYSTEINE (BPC) domain at their v…
Jul 2017 DOI 10.14302/issn.2574-4372.jesr-17-1705
Vijayalakshmi VarmaCorresponding author
Drug-induced cardiotoxicity is one of the predominant reasons for drug attrition and withdrawals. This is of critical concern when potentially cardiotoxic drugs are administered to individuals with inherited arrhythmogenic cardiac diseases or with metabolic diseases such as obesity and diabetes, whi…
Dec 2015 DOI 10.14302/issn.2470-5020.jnrt-15-701
Dao-Ming TongCorresponding author
This case contrasts reversible cerebral lesions with areas of irreversible necrosis following cardiorespiratory arrest. The authors discuss imaging evolution, mechanisms of hypoxic–ischemic injury, and implications for prognostication and rehabilitation.
Dec 2012 DOI 10.14302/issn.2326-0793.jpgr-12-101
Jian HanCorresponding author
Eukaryotic Signature Proteins (ESPs) are proteins that delineate the eukaryotes from the archaea and bacteria. They have no recognisable homologues in any prokaryotic genome, but their homologues are present in all main branches of eukaryotes. ESPs are thus likely to have descended from ancient prot…