Search results for “lung”

About 52 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching lung — open any to read the full text, or download the PDF or XML.

Clinical and Laboratory Predictors of Elevated TRV In Sickle Cell Anaemia

Jun 2018 DOI 10.14302/issn.2372-6601.jhor-18-2139
Jane S. Afriyie-MensahCorresponding author

Pulmonary hypertension (PH) has become an increasingly recognized complication in sickle cell anaemia (SCA) and is a major cause of morbidity and mortality. Though the burden of SCA in sub-Saharan Africa is high, there is paucity of data on SCA-associated PH with little or no attention given to it i…

Prenatal Prognostication of Congenital Diaphragmatic Hernia: What are we Looking at?

Dec 2017 DOI 10.14302/issn.2997-2086.jfs-17-1846
Ruchi AminCorresponding author

Introduction: Data support the use of both ultrasound (US) and magnetic resonance imaging (MRI) in the prenatal prognostication of congenital diaphragmatic hernia (CDH). The aim of this study was to examine our experience and learning curve with both of these diagnostic tools in the setting of a new…

Blockade of Programmed Cell Death Protein-1 Pathway for the Treatment of Melanoma

Nov 2017 DOI 10.14302/issn.2471-2175.jdrt-17-1760
Madhuri BhandaruCorresponding author

Metastatic melanoma is a very deadly type of skin cancer with poor prognosis and low 5-year survival rates. Until recently, patients with metastatic melanoma had very few treatment options, which only included dacarbazine and aldesleukin. In 2011, the first checkpoint blocker, ipilimumab was approve…

Development of a Chronic Obstructive Pulmonary Disease Severity Classification System Using A Japanese Health Insurance Claims Database

Sep 2017 DOI 10.14302/issn.2474-7785.jarh-17-1727
Manabu AkazawaCorresponding author

Background: Healthcare services provided to patients should vary depending on disease severity. However, disease severity bias, a type of selection bias, is a commonly encountered problem in administrative database studies. Herein, we selected chronic obstructive pulmonary disease (COPD), which comm…

Atypical Patterns of Constrictive Pericarditis after Heart Transplantation: A Case Report

Sep 2017 DOI 10.14302/issn.2576-9359.jot-17-1594
Osamu SeguchiCorresponding author

Constrictive pericarditis (CP) represents a rare complication after heart transplantation (HTx), resulting from various postoperative events such as mediastinitis, pericardial effusion, or allograft rejection. We describe our recent experience with managing an HTx recipient who developed atypical pa…

A Study on Contagious Bovine Pleuropneumonia in Khartoum State, Sudan

Aug 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1555
Isam KaramCorresponding author

The study was carried out to investigate the occurrence of contagious bovine pleuropneumonia CBPP in Khartoum state. One-hundred twenty-two pneumonic lung tissue samples were collected from different slaughterhouses (116 samples most of which from local breed cattle) and from the field (six samples…

Psychopathology of Brain Frontal Lobe Tumors : When the Neurosurgery Meets Psychiatry

May 2017 DOI 10.14302/issn.2694-1201.jsn-17-1470
Domenico ChirchigliaCorresponding author Professor of Department of Neurosurgery, University of Catanzaro

Brain tumors occur when abnormal cells form within the brain.There are two main types of tumors: malignant and benign tumors. Then, tumors can be divided into primary that start within the brain, and secondary tumors that have spread from somewhere else, known as brain metastasis tumors. Secondary b…

Repeat Thoraco-Amniotic shunt placement to treat Fetal Pleural Effusion due to Pulmonary Sequestration

Feb 2017 DOI 10.14302/issn.2997-2086.jfs-16-1098
Sathyaprasad BurjonrappaCorresponding author

We report a twin gestation with one fetus afflicted by a left sided Extra-Lobar Sequestration (ELS) in a morbidly obese mother. The ELS was complicated by a left pleural effusion in the second trimester unresponsive to maternal steroid administration. We discuss the need for repeat shunt placement,…

Performance Assessment of Some Operational Aspects of Revised National Tuberculosis Control Programme in Tuberculosis Unit, Nagpur, India

Feb 2017 DOI 10.14302/issn.2474-3585.jpmc-16-1103
Sanjeev M. ChaudharyCorresponding author

Background : DOTS is the current international strategy for tuberculosis control endorsed by the World Health Organization and the International Union against Tuberculosis and Lung Diseases. Maharashtra achieved full coverage under RNTCP in October 2003. The programme was launched in Nagpur in the l…

Obstructive Sleep Apnea Treatment with Epap Nasal Devices: Physiological Principles and Limitations

Jan 2017 DOI 10.14302/issn.2574-4518.jsdr-16-1333
T.S. HakimCorresponding author

Expiratory Positive airway pressure (EPAP) devices such as prevent have been used for treatment of obstructive sleep apnea without discussing their limitations. In this short review we discuss the physiological limitations of EPAP devices during inspiration and during expiration. During spontaneous…

Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression

May 2015 DOI 10.14302/issn.2471-7061.jcrc-14-574
Rosalyn B. IrbyCorresponding author

Colon cancer has a five-year survival of 64.7%, and about 50,000 people are expected to die from colon cancer this year. Patients with metastatic colorectal cancer have a significantly worse prognosis, a 12.9% five-year survival. This emphasizes the need for strategies to inhibit the growth and meta…

Differences in the Alveolar Macrophage Proteome in Transgenic Mice Expressing Human SP-A1 and SP-A2

Jul 2013 DOI 10.14302/issn.2326-0793.jpgr-13-207
Joanna FlorosCorresponding author

Surfactant protein A (SP-A) plays a number of roles in lung host defense and innate immunity. There are two human genes, SFTPA1 and SFTPA2, and evidence indicates that the function of SP-A1 and SP-A2 proteins differ in several respects. To investigate the impact of SP-A1 and SP-A2 on the alveolar ma…

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