Search results for “drug”

About 100 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching drug — open any to read the full text, or download the PDF or XML.

Malaria: A Driving Force to the Emergence and the Global Spread of Antibiotics Resistance

Mar 2025 DOI 10.14302/issn.2693-1176.ijgh-25-5429
Rasheed O. MakanjuolaCorresponding author

Malaria and bacteraemia are significant public health concerns and economic threats. In Africa, the intensity for simultaneous transmission and co-infection of Plasmodium spp and other bacteria pathogens are extremely high. It is believed that malaria suppress the immune system and enable the transl…

Creation of Music-Induced Analgesia in Chronic Pain Patients through Endogenous Opioid Production: A Narrative Review

Oct 2024 DOI 10.14302/issn.2688-5328.ijp-24-5319
Nivriti PuriCorresponding author

Chronic pain affects over 30% of the global population, and reliance on external drugs for treatment has led to major issues, including the present opioid epidemic. A healthier option is necessary, which is why music therapy’s analgesic effects have been extensively studied within the last 20 years.…

Genotypic Diversity among Salmonella Typhi Isolated from Children Living in Informal Settlements in Nairobi, Kenya

Sep 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5195
Susan Mutile KavaiCorresponding author

The persistence of multidrug-resistant (MDR) Salmonella Typhi (S. Typhi) is a challenge especially in regions where typhoid is endemic. Surveillance of circulating genotypes of MDR S. Typhi is crucial in typhoid acute cases and carriers. This study aimed to investigate genotypic diversity of S. Typh…

Prevalence and Antifungal Susceptibility of Candida species from patients attending Rivers State University Teaching Hospital, Nigeria

Sep 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5126
D. N Girah.Corresponding author

The development of medical therapy and patients profile has led to a rise in the incidence of nosocomial fungal infection. The frequency of candidiasis has surged worldwide, and the prevalent of healthcare diseases are now Candida species. Candida species causes a range of human infections known as…

Leflunomide-Induced Cystoid Macular Edema: A Rare Case Report

Aug 2024 DOI 10.14302/issn.2470-0436.jos-24-5162
João Alves AmbrósioCorresponding author

Introduction Cystoid macular edema (CME) is a sight-threatening condition caused by fluid accumulation in the macula due to blood-retinal barrier disruption. Various factors, including drug reactions, can lead to retinal fluid leakage. Leflunomide, a disease-modifying anti-rheumatic drug, marked sig…

The Beneficial Effect of Two Nutraceuticals in Flea Allergy Dermatitis Itch Control: A Comparative Study

May 2024 DOI 10.14302/issn.2379-7835.ijn-24-5098
Luisa CorneglianiCorresponding author

This prospective randomized double-blinded multicentric study aimed to assess the efficacy of a new nutraceutical in controlling itch and skin lesions caused by flea allergy dermatitis (FAD) and compare it with another oral product of proven efficacy. Forty-three dogs, of different age, breed and se…

A Network Pharmacology-Based Strategy For Predicting Therapy Targets Of Beta-Sitosterol In Treating Diabetic Retinopathy

May 2024 DOI 10.14302/issn.2470-0436.jos-23-4493
Kexin SunCorresponding author

Background Beta-Sitosterol (SIT) is an active TCM compound employed to treat diabetic retinopathy (DR). A network pharmacology approach to understanding the active ingredients and the therapeutic mechanisms underlying DR has not been pursued. Methods The potential targets for DM were identified acco…

Fecal Shedding, Antimicrobial Resistance and In Vitro Biofilm formation on Simulated Gallstones by Salmonella Typhi Isolated from Typhoid Cases and Asymptomatic Carriers in Nairobi, Kenya

Apr 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5030
John S. GunnCorresponding author

Typhoid fever, caused by the human restricted pathogen Salmonella Typhi, remains a major global public health concern. Even after successful treatment, approximately 3-5% of patients with typhoid fail to clear the bacteria within one year and become chronic carriers. Most typhoid carriers have galls…

Edpidemiology, Clinical Profile and Short- Term Outcome of Hypertensive Crisis in N'Djamena (Chad)

Apr 2024 DOI 10.14302/issn.2329-9487.jhc-24-5040
Dangwe Temoua NaibéCorresponding author

Objective Hypertensive crisis is an increasingly frequent medical condition in our context. Its management in medical emergencies is a real challenge for physicians. Few data on hypertensive crisis are available in Chad. The aim of this study was to investigate the epidemiological, clinical and prog…

RETRACTED: A Microglia Initiated Target Therapy in Neuroinflammation for Alzheimer’s Patients

Apr 2024 DOI 10.14302/issn.2998-4211.jalr-24-4926
Bahadur Khan FaizaCorresponding author

This article has been retracted on 20 March 2025. VIEW THE RETRACTION NOTICE (https://doi.org/10.14302/issn.2998-4211.jalr-25-5855) The research is focused on neuroinflammation a normal physiological process which is known to be associated with neurodegenerative diseases could be the potential targe…

Challenges in Diagnosis of Neurosarcoidosis

Mar 2024 DOI 10.14302/issn.2694-1201.jsn-22-4184
Adel EkladiousCorresponding author

Sarcoidosis is granulomatous autoinflammatory autoimmune remitting relapsing disease affecting every organ in the body, it is the most difficult disease to diagnose in the absence of serum or imaging biomarker. Differential diagnosis is broad which included inflammatory, infective, neurodegenerative…

Antibiotic Prescribing Practices for Upper Respiratory Tract Infection Among Clinical Officers at Kiambu County

Mar 2024 DOI 10.14302/issn.2640-690X.jfm-24-5016
Kevin MurigiCorresponding author

Background Antibiotics are the most prescribed medications worldwide. Global consumption rose by 65% in 76 low and middle-income countries between the years 2000 and 2015. According to the World Health Organization, improper administration of antibiotics occurs in over 60% of people with upper respi…

A Study on Nutraceuticals

Mar 2024 DOI 10.14302/issn.2379-7835.ijn-24-4921
Manya BajajCorresponding author

Hippocrates trusted foodstuff, maybe medicine, and healthcare management, administration, and costing are important. Nutraceuticals, derived from "nutrition" and "pharmaceutical," cover differing healing areas like “antagonistic-hard, cold and cough, sleep difficulties, digestion, cancer prevention,…

The Role of Non-Pharmacological Interventions for Disrupted Sleep in the Moderate-Severe Dementia Population: A Systematic Review

Feb 2024 DOI 10.14302/issn.2998-4211.jalr-23-4813
Esther del Carmen Teruel HernándezCorresponding author

This study systematically reviews the literature on non-pharmacological interventions for disrupted sleep-in people meeting established criteria for moderate-severe dementia, and to analyze the methodological quality of the included studies. The PubMed, PEDro, Cochrane, Virtual Health Library, APA P…

Understanding Reasons for Lack of Effectiveness of National TB Program in Peru: Qualitative Analysis of MDRTB Control

Jan 2024
Selene MangaCorresponding author

Drug-resistant tuberculosis (DR-TB) is the most urgent public health problem to solve in Peru, according to the Ministry of Health 1. In the WHO Global TB Report 2021, Peru has the highest burden of DR-TB in the Americas (Table 1), with 38% of TB cases either RR or MDR. In addition, the Ministry rep…

Study of Anti-Inflammatory Effects of Black Cumin (Nigella Sativa) and Honey on Mice (Mus Musculus)

Aug 2023 DOI 10.14302/issn.2694-2275.jzr-23-4642
Tayyaba ZahoorCorresponding author

The study was conducted to determine the effect of Nigella sativa (Kalonji) and Honey as an anti-inflammatory agent for humans and animals. The study was carried out on 20 Albino Mice of almost equal size and weight. All the mice were given 5% solution of formalin in a dose of 0.5ml injection in the…

A Newer Approach in the Management of Cough: A Review on Levodropropizine

May 2023 DOI 10.14302/issn.2642-9241.jrd-23-4566
Krishna C VeligandlaCorresponding author

Safe and effective antitussive therapy remains a significant area of unmet need for cough management. Antitussive drugs are commonly used cough suppressants and include centrally acting (opioids and non-opioids) cough suppressants and peripherally acting antitussives. Authors searched PubMed, Google…

Safety of BBIBP-CorV (Sinopharm) COVID-19 Vaccination in People With Multiple Sclerosis: A Report From Iran

Mar 2023 DOI 10.14302/issn.2690-4837.ijip-22-4342
Seyed Massood NabaviCorresponding author

Introduction Vaccination against SARS CoV-2 started on March 2020 in Iran and people with multiple sclerosis (pwMS) have a priority to be vaccinated in line of other high-risk population. Up to now, BBIBP-CorV (Sinopharm) is the main vaccine which have been used in Iranian population, and in high ri…

Effect of Extracts of Dialium guineense Stem Bark on Lipid Profile and CCl4- Induced Histological Changes in Liver of Wistar Rats

Nov 2022 DOI 10.14302/issn.2835-513X.ijl-22-4266
O.D AbuCorresponding author Department of Biochemistry, Faculty of Life Sciences, University of Benin, Benin City, Nigeria

The present study investigated the effect of aqueous and ethanol extracts of Dialiumguineense stem bark on lipid profile and CCl4- induced histological changes in liver of Wistar rats. Adult male Wistar rats (n = 25) weighing 160 – 180 g (mean weight = 170 ± 10 g) were randomly assigned to five grou…

Correlating 13C Isotope in Oligomeric Proanthocyanidins with their Anticancer Properties

Oct 2022 DOI 10.14302/issn.2572-3030.jcgb-22-4284
Reginald B. LittleCorresponding author

Upon considering the anticancer effects of larger oligomeric proanthocyanidins and observing various papers reporting the high resolution mass spectroscopy of the oligomeric proanthocyanidins, it is determined that the unusual 13C enrichment in some plant oligomeric proanthocyanidins may be responsi…

Frequently asked questions

Are these articles peer-reviewed?
Yes. Articles published at Open Access Pub go through single-blind peer review (double-blind on request) under an editorial board before publication.
Are the articles free to read?
Yes. Every article is open access — read the full text online for free and download the PDF or XML, with no paywall or subscription.
How do I cite an article?
Use the DOI shown on each result and on the article page; it is the permanent, citable link to the article.
How do I read or download an article?
Click "Read full text" to open the article HTML, or use the PDF / XML buttons on each card to download it.