- Open access · CC BY 4.0
- Published by Open Access Pub
About the In-vitro In-vivo In-silico Journal
The In-vitro In-vivo In-silico Journal (IIIJ) is a peer-reviewed, open-access journal of research on the discovery, development and delivery of new drugs. It reads three kinds of evidence together: laboratory studies in vitro, studies in living organisms in vivo, and computational work in silico.
Three lenses
Three kinds of evidence, read together
The journal is named for its method. Each lens answers a different question about a candidate drug, and the strongest work connects them.
In vitro
Laboratory evidence
Cell-based, biochemical and other bench assays that characterize how a compound acts and what it does to its target.
In vivo
Evidence from living organisms
Studies in animal models and other organisms of pharmacokinetics, efficacy, safety and toxicology.
In silico
Computational evidence
Modeling, simulation, cheminformatics and data-driven methods that predict, prioritize and explain.
Purpose and readership
Evidence for new therapies
The In-vitro In-vivo In-silico Journal (IIIJ) publishes research that uses in-vitro, in-vivo and in-silico approaches to discover, develop and deliver new drugs, with drug discovery and development as its core. The journal considers pharmacology, pharmacokinetics, toxicology, structure–activity relationships, efficacy, safety, and the cost and benefit evaluation of new drugs.
Related work in the life sciences is welcome, including molecular and cell biology, physiology, biochemistry, bioinformatics and regenerative medicine, when it bears on how new therapies are discovered, tested or delivered. The Aims and Scope page describes the scope in full.
The journal serves researchers in pharmaceutical and biomedical sciences, medicinal chemists, toxicologists, computational scientists and clinicians who need sound preclinical and translational evidence, and makes the results freely available to everyone who can use them.
Article types
- Original Research
- Review
- Systematic Review and Meta-Analysis
- Methods
- Short Communication
- Data Note
- Case Report
- Commentary
- Letter
Preparation guidance for each type is given in the Instructions for Authors.
Journal register
Journal register
Reference information on the journal’s ownership, editorial responsibility, rights, review, fees and preservation.
- Full title
- In-vitro In-vivo In-silico Journal
- Short title IIIJ.
- Publisher and owner
- Open Access Pub
- The journal is owned and published by Open Access Pub. openaccesspub.org
- Publication history
- Since 2018
- Volume 1, Issue 1 of the journal was first published on May 6, 2018.
- Access
- Open access
- Every article is free to read, download and share from the day of publication, with no subscription or registration.
- License and copyright
- CC BY 4.0
- Articles are published under the Creative Commons Attribution 4.0 International license. Authors retain copyright.
- Peer review
- Single-blind by default
- Single-blind by default; double-blind review is available on request.
- Article processing charge
- USD 1,200
- Payable only after acceptance; withdrawal after submission is subject to the journal’s withdrawal policy.
- Research integrity
- Crossref Similarity Check
- Submitted manuscripts are screened with Crossref Similarity Check, powered by iThenticate.
- Preservation
- Portico
- The journal’s content will be deposited in Portico, the digital-preservation archive run by ITHAKA.
Editorial process
From submission to publication
- 1SubmitAuthors submit through ManuscriptZone, the simple submission form or the editorial office.
- 2ScreeningThe editorial office screens each submission against scope and minimum requirements.
- 3Peer reviewManuscripts that proceed are evaluated by independent subject-matter experts.
- 4DecisionThe handling editor decides, under the oversight of the Editor-in-Chief.
- 5PublicationAccepted articles are published open access under CC BY 4.0.
Ready to submit? Read the Instructions for Authors, then use the Submit Manuscript page. Questions can be sent to info@openaccesspub.org.